The precision in formation of a developing embryo is the result of an intricate mechanism of morphogenetic events, which bring cell populations together for interactions to form three dimensional structures. Complex cascades of signal transduction pathways coupling with an overlapping array of transcription factors constitute the basis for interpreting the transient morphogenetic code. Chrissa Kioussi focuses on the molecular mechanisms by which transcription factors, such as the homeobox genes, mediate cardiovascular and muscle development. Using mouse model systems she searches for a better understanding of congenital heart diseases, muscular dystrophies and human syndromes.
College of PharmacyOregon State UniversityCorvallis, OR 97331Phone: 541.737.3424Fax: 541.737.3999