We are studying tissue regeneration and wound-healing using mice-models and 3D-human bioprinted skin. We utilize biodegradable nanofibers loaded with growth-factors, anti-microbial peptides and exosomes for efficient healing of chronic wounds in diabetes and hypoxia. Anti-cancer, anti-aging and anti-oxidant effects of bioactive compounds from hemp, hops and meadowfoam are being investigated.
Dr. Irwin is trained in pharmacy practice research and has research interests in methods to justify clinical pharmacy services including quality measures and various evolving payment models. Her work has been funded by multiple organizations and she has contributed over 20 peer-reviewed publications.
Dr. Ishmael’s research focuses on the use of new chemical entities from marine organisms and fungi as tool compounds to disrupt cell signaling and proteostasis in human cancer cells. With a special interest in glioblastoma, our goal is to identify and validate novel druggable targets for the treatment of human disease.
The Kioussi laboratory is interested in defining the gene regulatory networks involved in organ development and energy balance systems. Their studies serve as the foundation for development of future strategies and pharmacological interventions that influence the maintenance and differentiation potential of cell populations in patients with congenital defects and disrupted metabolic fuel homeostasis.
Taifo Mahmud’s research interests focus on natural product-based drug discovery and development. His group employs a multidisciplinary approach that utilizes cutting-edge technologies to produce novel pharmaceuticals. Some recent accomplishments of his group include discovering new families of enzymes and developing antimalarials, anti-cancers, and sunscreens through genetic engineering or synthetic biology.
AI Integration: Exploring the implementation of AI in streamlining IT operations, enhancing cybersecurity, and automating routine tasks.
Innovation in IT: Investigating how AI-driven analytics can predict IT system failures and optimize maintenance schedules.
AI Ethics: Addressing the ethical considerations and best practices for deploying AI in sensitive IT environments.
Future Trends: Analyzing upcoming trends in AI that could revolutionize the IT consultancy landscape.
Our efforts are focused on the understanding how the interplay between host and microbiota contributes to pathogenesis and treatment of diseases such as type 2 diabetes, NASH, IBD, immunodeficiency, and cancer. This is a highly collaborative effort involving advanced causality inference and network analyses of multi-omics data coupled with gnotobiotic animal models, observational and interventional (i.e. clinical trials) studies in patient populations.
