Indra Team

Arup Indra Smiling at camera

Arup Indra, Ph.D. 

Primary Investigator

Professor of Pharmacology at OSU, Associate Professor (Adjunct) in the Department of Dermatology at OHSU, Member of the Consortium for Natural Products Drug Discovery, Member of Knight Cancer Institute, Affiliate Investigator at Linus Pauling Institute

Research interests:

  • Finding novel cancer biomarkers used for earlier diagnosis and prediction of disease progression in human head and neck cancers
  • Creating nanobiosensors used for earlier diagnosis and prediction of human cancers
  • Identifying changes in lipid profiles from patients with eczema, atopic dermatitis, and allergic contact dermatitis using lipidomic analysis
  • Characterizing novel signature alterations and mutations during both spontaneous and UV-induced melanoma progression in humans for better diagnosis and treatment options
  • Identifying novel signals through microRNA profiles in differing skin cells of psoriasis patients

Contact: [email protected]

Ebunoluwa Morakinyo smiles at camera

Ebunoluwa Mercy Morakinyo

Undergraduate Student from the Honors College and College of Science, studying Biochemistry and Molecular Biology with Pre-Medicine option. Plans to pursue a medical degree and hopefully train to become a physician-scientist.

Research Interest:

  • Determine function of stem cells in hair cycling and immune-cells during wound healing.
  • Characterization of nanofiber mediated delivery and sustained release of bioactive molecules (BAMs) with anti-inflammatory and anti-microbial properties and ability to promote wound healing.  

Contact: [email protected]

Sofia Dixon smiling at camera

Sofia Dixon

Undergraduate Student from the Honors College and College of Science majoring in Bio-health Science. Joined the lab in 2021 through a competitive URSA engage program. Plans to pursue an advanced degree in Pharmaceutical  Sciences and/or medicine.

Research Interest:

  • Identify and characterize new mechanisms of signaling between epithelial, endothelial and immune cells during wound healing and tissue remodeling.

Contact: [email protected]

gitali indra smiles at camera

Gitali Ganguli-Indra, Ph.D.

Associate Professor of Pharmacology

Member of Knight Cancer Institute, Affiliate Investigator at Linus Pauling Institute

Research interests:

  • Identifying and characterizing factors that can impact cutaneous wound healing through the mobilization of stem cells as well as the understanding of their molecular mechanisms
  • Identifying novel therapeutic targets for cancers of the head,neck, prostate, lung, pancreas, and skin

Contact: [email protected]

Cara Baboyan smiles at camera in outdoors

Cara Baboyan

Undergraduate Student from the Honors College and College of Science majoring in Biochemistry and Molecular Biology. Joined the lab in 2021 through a competitive URSA engage program. Plans to pursue a Pharmacy degree and hopefully train to become a clinical Pharmacist in Pharmaceutical Industry.  

Research Interest:

  • Isolation and  characterization of extracellular vesicles (EVs) including exosomes derived from mesenchymal stem cells for therapeutic interventions against cancer in feline and canine species.
  • Loading of stem cells derived exosomes with chemotherapeutic drugs and determine their function in reducing cardiotoxicity and enhancing selectivity.

Contact: [email protected]

Anna Nielsen smiles at camera

Anna Nielsen

Undergraduate Student from the Honors College and College of Science majoring in Biology. Joined the lab in 2021 through a competitive URSA engage program. Plans to pursue an advanced degree in Pharmaceutical Sciences and/or medicine.

Research Interest:

  • Screening of bioactive natural compounds isolated from meadowfoam (Limnanthes alba), hemp (Cannabis sativa) and ayurvedic plants such as ashwagandha (Withania somnifera) to establish their anti-cancer, anti-ageing, anti-oxidant, anti-inflammatory and immunomodulatory properties.  

Contact: [email protected]

Sai Singh smiles at camera

Sai Singh

Undergraduate Student, Lab assistant from the College of Science, BioHealth Science Major

Research Interest

  • Characterizing animal models of human skin diseases with pigmentation disorder e.g. vitiligo and those with increased susceptibility to UV-induced melanoma development.

Contact: [email protected]


Previous Team Members

Post Doc Researchers

Sergiy Kyryachenko

Joined the lab as a Post Doc

Research focuses:

  • RXRa mediated cell signaling and molecular networking during melanocyte homeostasis
  • Role of VDR signaling in melanocytes in controlling DNA damage, DNA repair, and melanomagenesis

Gunjan Guha

Joined the lab as a Post Doc

Research focuses:

  • CTIP2 mediated cell signaling and molecular networking during dermal homeostasis
  • Role of keratinocytic CTIP2 in wound healing
  • Role of biosynthetically engineered novel pactamycin analogs in prevention of head and neck cancer in melanoma prevention

Gaurav Bajaj

Joined the lab as a Post Doc

Research focuses:

  • Stem cells and wound healing

Hyo-Sang Jang

Joined the lab as a Post Doc

Research focuses:

  • Transcriptional control of cutaneous wound healing

Ling-Juan Zhang

Joined the lab as a Post Doc

Research focuses:

  • CTIP2 mediated cell signaling and molecular networking during epidermal homeostasis
  • Role of keratinocytic CTIP2 skin inflammation
  • Hair cycling

Jeffrey Burnett

Joined the lab as a Visiting Scholar

Research focuses:

  • Biomarker development and the HNSCC
  • Identification of novel biomarkers for lung, cervical, and prostate cancer

Priti Bala Singh

Joined the lab as a Visiting Scholar

Research focuses:

  • Melanocytic RXRa signaling in melanocyte homeostasis and UV induced melanomagensis
 

Graduate Students

Canan Schumann

Joined the lab as a Pharm. D. student

Research focuses:

  • Role of HGF and ET-1 signaling in UV induced melanomagenesis

Stephen Hyter

Joined the lab as a graduate student

Research focuses:

  • Nuclear receptor signaling in the tumor microenvironment during melanomagenesis
  • Role of endothelin signaling during UV induced melanocyte activation
  • Transcriptional network in regulating keratinocyte-derived paracrine signaling

Zhixing Wang

Joined the lab as a graduate student

Research interests:

  • Transcriptional regulation of epidermal lipid metabolism and barrier functions
  • Role of novel natural compounds on epidermal homeostasis and barrier maintenance

Daniel Coleman

Joined the lab as a graduate student

Research focuses:

  • Nuclear receptor signaling in the tumor microenvironment during melanomagenesis
  • Role of natural compounds in targeting melanoma stem and progenitor cells

Lalithambigai Ananthal

Joined the lab as a graduate student

Research focuses:

  • Characterization of a pair of monoclonal antibodies against nicotinamide nucleotide transhydrogenase (NNT)

Shreya Bhattacharya

Joined the lab as a graduate student

Research focuses:

  • Transcriptional regulation of adult skin homeostasis
  • Cross talk between epidermal keratinocytes and dermal fibroblasts

Sharmeen Chagani

Joined the lab as a Rotation Graduate Student

Research focuses:

  • Characterization of solar UV induced melanoma in a novel preclinical murine model
  • Screening and identification of novel natural compounds with anticancer effects against HNSCC

Evan Carpenter

Graduate Student, Ph.D. Graduated 2022

Research interests:

  • Melanocyte physiology in the context of the prevention and treatment of melanoma
  • Anti-cancer drug screening
  • Reduction/oxidation signaling in melanocyte homeostasis and melanomagenesis

Undergraduate Students

Heather Wheeler

Joined the lab as an undergraduate student

Research focuses:

  • Bio-informatics based approaches for analyzing ChIP-seq and RNA-seq data obtained after next generation sequencing

Anna-Marie Sherman

Joined the lab as an undergraduate student

Research focuses:

  • Immunohistochemical characterization of melanoma tumors in preclinical animal models

Steven Ma

Joined the lab as an undergraduate student

Research focuses:

  • UV and ET-1 mediated paracrine regulation of melanocyte homeostasis

Talicia Savage

Joined the lab as an undergraduate student

Research focuses:

  • Role of CTIP2 in cutaneous wound healing

Vannah Nguyen

Joined the lab as an undergraduate student

Research focuses:

  • Expression studies of nuclear hormone receptors in pre-clinical melanoma models and in human melanomas
 

Research Staff

Xiaobo Liang

Joined the lab as a Faculty Research Assistant

Research focuses:

  • Maintenance of genetically engineered mice
  • Training undergraduate and graduate students in practical hands-on techniques
  • Technical support for ongoing projects