arup indra smiles at camera

Arup Indra

Professor

Research/Career Interests

Research Areas
  • Skin development and stem cell biology
  • Inflammatory skin diseases
  • Melanoma and tumor microenvironment
  • Transcriptional regulation in skin
Key Investigations
  • Mechanisms of skin barrier formation and maintenance
  • Role of Ctip2/Bcl11b in skin development
  • Lipidomics profiling in atopic dermatitis
  • Nuclear receptor signaling in melanoma progression
  • UV-induced skin tanning and photoaging
Models and Approaches
  • Mouse genetics
  • Biochemical, cellular, and molecular techniques
  • Pre-clinical models of skin diseases (ichthyosis, atopic dermatitis, pigmentation disorders, invasive melanomas)
Collaborative Projects
  • Biomarker development for head and neck cancers
  • Nano-biosensors for cancer detection
  • Lipidomics in eczema and dermatitis
  • Melanoma progression signatures
  • MicroRNA profiling in psoriasis

The laboratory combines basic science with translational research, focusing on understanding skin development, disease mechanisms, and cancer progression, with the goal of developing new diagnostic tools and therapeutic interventions

Lab Page

Credentials

  • Senior Research Scientist, IGBMC, France, 2002–2005 
  • Postdoctoral Fellow, IGBMC, France, 1997–2001 
  • Ph.D., Jadavpur University, Kolkata, India 2001 
  • M.S., Calcutta University, India, 1992
Contact

1601 SW Jefferson Avenue
Pharmacy Building 325
97331 OR
United States

Research Topics & Highlights
Research Highlights

The Indra laboratory is investigating the mechanisms underlying the crosstalk between skin-cells and role of microenvironment in atopic-dermatitis, vitiligo, tumor-heterogeneity and in metastatic melanoma. We discovered different factors that regulate UV-induced melanocyte/epidermal stem-cell survival, proliferation and migration. The anti-cancer, anti-oxidant, anti-inflammatory and anti-ageing effects of bioactive natural compounds are further studied.